@article{3071, author = {H Schwermer and F Brülisauer and A De Koeijer and D Heim}, title = {Evaluation of the effectiveness of selected measures against Bovine Spongiform Encephalopathy (BSE) in Switzerland by use of the basic reproduction ratio R0}, abstract = {The effectiveness of two measures against Bovine Spongiform Encephalopathy (BSE), the compulsory processing of animal by products to meat and bone mea (MBM) at 133 °C under 3 bars of pressure for 20 minutes in February 1993 and the exclusion offallen stock, heads with eyes and spinal cord of cattle older than 30 month from MBM production in April 1996, was evaluated in a process model. The transmission of BSE by calculation of the basic reproduction ratio R0 was modelled.The results were verified by use of a cohort model, based on observed surveillance data. Prior to 1990, before the ban of feeding MBM to ruminants, R0, as calculated in the process model, was above 1,coherent with a slowly progres-sing BSE epidemic. Since 1991, values of R0 were lowat 0.06.The corresponding Rc values derived from the cohort model were higher, the lowest value 0.13 calculated for 1996. Given such low R0 values, the epidemic should have died out. Addi-tionally, no influence of the two measures was obvious at that time given the low level of R0.The discrepancy between the results of the two modeis is evidence for a dependency of the BSE epidemic from an infection source not considered in the process model.This infection source is most likely importation of feed ingre-dientsandMBM.}, year = {2007}, journal = {Berliner und Münchener Tierärztliche Wochenschrift}, volume = {120}, pages = {189-196}, month = {05/2007}, publisher = {Schlütersche Verlagsgesellschaft mbH & Co. KG}, address = {Hannover}, issn = {0005-9366}, doi = {10.2376/0005-9366-120-189}, language = {English}, }